Guy Ashad served as principal flutist in the Maggio Musicale Fiorentino Orchestra conducted by Zubin Mehta, the Berlin State Orchestra conducted by Daniel Barenboim, the Swedish Radio Symphony Orchestra conducted by Daniel Harding and the Manchester Camerata Orchestra conducted by Douglas Boyd. After his military service, he was the principal flutist in the Haifa Symphony Orchestra and since 2001 he is the principal flutist of the Divan East West Orchestra under the direction of Daniel Barenboim. He is regularly invited to play as guest principal flutist with various orchestras, including the Bavarian Radio Orchestra, the Los Angeles Philharmonic, the Mahler Chamber Orchestra, the London Philharmonic, the Rotterdam Philharmonic, the Bamberg Symphony and the La Scala Orchestra. As a soloist, he has performed with orchestras in Israel, including the Israel Philharmonic, and in Europe,  the prestigious Salzburg and Lucerne festivals. As a chamber music player he was a founding member of Ensemble 360 (England), with whom he also recorded, participated in important festivals and performed with renowned artists, including Daniel Barenboim, Elena Bashkirova, Kirill Gerstein, Guy Braunstein and the soloists of the Berlin Philharmonic. He also recorded for BBC radio stations, Sweden, Germany and Israel and released four CDs. Guy Eshed regularly won scholarships from the America-Israel Cultural Foundation and received a special grant of excellence from the Toepfer Foundation in Hamburg.